According to Wikipedia, trepanation involves drilling or scraping a hole into the human skull. A fun fact that makes it the perfect title for this psychotropic anime-flavored video for the Japanese creative collective Millennium Parade.

Directed by Ryoji Yamada thru his Tokyo prodco mimoid for producer/musician Daiki Tsuneta, the video asks, “What do androids think the moment they get their ego?”. Then answers, “A human heart that springs up and a strong awareness that you cannot become a human.”
 

Label: Sony Music Japan
Artist: Millennium Parade

Production: mimoid
Director: Ryoji Yamada
Creative Director: Shu Sasaki (Millennium Parade / PERIMETRON)
Producer: Hiroshi Yamakawa (MULTRA)
Animator: Yasuhiro Tomita, Ryoji Yamada (mimoid), Hideki Inaba (mimoid), Masanobu Hiraoka (mimoid), Tetsuya Tatamitani
Tatsuhiro Ariyoshi, Yurika Someya, Choi seo yeon, Tomoe Obayashi, Miho Kidoguchi
Color Artist: Wakana Kuraguchi, Rina Koide, Ai Takeda
Compositor: Shohei Inayoshi, Mina Sanda
Concept Artist: Tomoya Sato (WACHA JACK), Sha Sanzen (WACHA JACK)
Online Editor: Takahiro Ota (KASSEN)
Production Manager: Upcoming Imoto